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Obagi-C® Rx System - Normal to Dry
Obagi-C® Rx System - Normal to Dry
A complete skin-care regimen specifically formulated for normal to dry skin with 4% hydroquinone to reduce hyperpigmentation, and other key ingredients, such as Vitamin C, to maintain the appearance of younger-looking skin.
Prescription required. Contact your healthcare provider to purchase, or find a nearby physician who offers this product.
Skin Type: Dry Skin, Normal Skin
Skin Concerns: Hyperpigmentation and Melasma, Skin Discoloration
System
- Size 5 pieces







Obagi-C Rx Systems promote skin rejuvenation from the inside out using a formulation of prescription-strength hydroquinone, 4%, which reduces the appearance of hyperpigmentation, combined with 10% ascorbic acid, a powerful anti-oxidant known to support and defend the skin against future damage.
System Includes:
- C-Cleansing Gel (6 FL. OZ.)
- C-Clarifying Serum Normal to Dry* (1 FL. OZ.) Rx Only
- C-Exfoliating Day Lotion (2 FL. OZ.)
- C-Therapy Night Cream*† (2 OZ.) Rx Only
- Sun Shield Matte Broad Spectrum SPF 50 (3 OZ.)
*Valid prescription required. Please see Prescribing Information for Obagi-C Rx System.
† Contains sodium metabisulfite, a sulfite that may cause allergic-type reactions, including anaphylactic symptoms and life-threatening or less severe asthmatic episodes in certain susceptible people. The overall prevalence of sulfite sensitivity in the general population is unknown and probably low. Sulfite sensitivity is seen more frequently in asthmatic than in non-asthmatic people.
With a 30-year legacy of science and innovation, Obagi has led transformative research that has met the needs of every skin tone and type. We believe skin care is more than “correcting” or even “preventing,” it’s about unleashing your skin’s full potential. That’s why at Obagi we create inclusive products that support the diversity we all bring to the table. It’s about developing scientifically backed, clinical-quality formulations to promote healthy-looking, future-facing skin.
NEED TO KNOW
Important Safety Information: Obagi-C Rx C-Therapy Night Cream (contains 4% hydroquinone)
CONTRAINDICATIONS: People with prior history of sensitivity or allergic reaction to this product or any of its ingredients should not use it. The safety of topical hydroquinone use during pregnancy or in children (12 years and under) has not been established.
WARNINGS:
- Avoid contact with eyes, nose, mouth, or lips. In case of accidental contact, patient should rinse eyes, nose, mouth, or lips with water and contact physician.
- Sunscreen use is an essential aspect of hydroquinone therapy because even minimal sunlight exposure sustains melanocytic activity.
- Contains sodium metabisulfite, a sulfite that may cause allergic-type reactions including anaphylactic symptoms and life-threatening or less severe asthmatic episodes in certain susceptible people. The overall prevalence of sulfite sensitivity in the general population is unknown and probably low. Sulfite sensitivity is seen more frequently in asthmatic than in nonasthmatic people.
PRECAUTIONS (ALSO SEE WARNINGS): Treatment should be limited to relatively small areas of the body at one time since some patients experience a transient skin reddening and a mild burning sensation, which does not preclude treatment.
Pregnancy Category C: Animal reproduction studies have not been conducted with topical hydroquinone. It is also not known whether hydroquinone can cause fetal harm when used topically on a pregnant woman or affect reproductive capacity. It is not known to what degree, if any, topical hydroquinone is absorbed systemically. Topical hydroquinone should be used on pregnant women only when clearly indicated.
Nursing Mothers: It is not known whether topical hydroquinone is absorbed or excreted in human milk. Caution is advised when topical hydroquinone is used by a nursing mother.
Pediatric Usage: Safety and effectiveness in children below the age of 12 years have not been established.
Use of the product should be discontinued if hypersensitivity to any of the ingredients is noted.
Hydroquinone 4%
Strong inhibitor of melanin production that has long been established as the most effective ingredient for reducing and potentially eliminating melasma.
L-Ascorbic Acid
Known as the purest form of Vitamin C, L-ascorbic acid helps neutralize free radicals, minimize the look of fine lines and wrinkles, and brighten skin tone.
Daily Use of Vitamin C
- Proactively fortifies the skin's defenses against environmental assaults
- Encourages skin to rebound from previous, visible damage for an improved appearance of fine lines, wrinkles and dark spots
- Aids in restoring skin's antioxidant strength to help skin appear younger for longer
Obagi-C® Cleansing Gel
Purified water, sodium lauroyl oat amino acids, cocamidopropyl betaine, sodium laureth sulfate, aloe barbadensis leaf juice, medicago sativa (alfalfa) extract, borago officinalis (borage) extract, chamomilla recutita (matricaria) flower extract, sodium chloride, saponins, xanthan gum, L-ascorbic acid (vitamin C), phenoxyethanol, methylparaben, ethylparaben, butylparaben, propylparaben, isobutylparaben, glycerin, fragrance, D&C red no. 33, FD&C yellow no. 5
Obagi-C® Rx C-Clarifying Serum
Active Ingredient: Hydroquinone USP, 4% (40 mg/g)
Inactive Ingredients: Water (aqua), propylene glycol, alcohol denat., dipropylene glycol,
ascorbic acid, propylene carbonate, sodium lauryl sulfate, fragrance
Obagi-C® C-Exfoliating Day Lotion
Purified water, glycolic acid, arginine, hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer, squalane, polysorbate 60, ethylhexyl palmitate, ethylhexyl stearate, caprylic/capric triglyceride, isopropyl palmitate, glyceryl stearate, PEG-100 stearate, PEG-8 dimethicone, PEG-8 ricinoleate, sodium hyaluronate (hyaluronic acid), sodium hydroxide, glycerin, ascorbyl glucoside (vitamin C), tocopheryl acetate (vitamin E), phenoxyethanol, cetearyl alcohol, ceteareth-20, dimethicone, steareth-2, tetrasodium EDTA, bisabolol, methylparaben, ethylparaben, butylparaben, propylparaben, isobutylparaben, fragrance
Obagi-C® Rx C-Therapy Night Cream:
Active Ingredient: Hydroquinone USP, 4% (40mg/g)
Inactive Ingredients: Water (aqua), glycerin, cetyl alcohol, PPG-2 myristyl ether propianate, sodium lauryl sulfate, TEA-salicylate, latic acid, phenyl trimethicone, tocopheryl acetate, sodium metabisulfite, ascorbic acid, methylparben, disodium EDTA, propylparaben, saponins, BHT
Sun Shield® Matte Broad Spectrum SPF 50
Active Ingredients: Homosalate 10%, Octisalate 5%, Zinc Oxide 16.5%
Inactive Ingredients: Water (Aqua), C15-19 Alkane, Octyldodecyl Neopentanoate, Polymethylsilsesquioxane, Sorbitan Olivate, Silica, Polyglyceryl-6 Polyrininoleate, Sodium Chloride, Xanthan Gum, Glycerin, Hydroxyacetophenone, Disodium EDTA, 1,2-Hexanediol, Caprylyl Glycol, Sodium Hydroxide, Triethoxycaprylsilane, Polyhydroxystearic Acid, Disteardimonium Hectorite, Polyglyceryl-2 Isostearate, Euphorbia Cerifera (candelilla) Wax, Beeswax, Dimethicone.
Morning Routine:
Step 1: Apply C-Cleansing Gel
Step 2: Apply C-Clarifying Serum - Normal to Dry
Step 3: Apply C-Exfoliating Day Lotion
Step 4: Apply Sun Shield Matte Broad Spectrum SPF 50
Nighttime Routine:
Step 1: Apply C-Cleansing Gel
Step 2: Apply C-Clarifying Serum - Normal to Dry
Step 3: Apply C-Therapy Night Cream
- Sun exposure should be limited by using a sunscreen agent or protective clothing to cover bleached skin when using and after using this product in order to prevent darkening for reoccurring.
- Using a broad-spectrum sunscreen SPF 30 or higher together with a comprehensive sun protection program including wearing sun protective clothing, hats, sunglasses, and avoiding the sun between the hours of 10am - 2pm may help reduce the risk of premature skin aging.
- Please see above for additional important safety information.
- Store at controlled room temperature: 15°C–25°C (59°F–77°F)
- Keep out of direct sunlight



Before, Meet After
Before, Meet After
87%
Overall Pigmentation Intensity
80%
Overall Photodamage
90%
Tactile Roughness
50%
Fine Lines and Wrinkles
87%
Overall Pigmentation Intensity
80%
Overall Photodamage
90%
Tactile Roughness
50%
Fine Lines and Wrinkles