Target. Treat. Transform. Clenziderm Pore Therapy liquid exfoliant tackles blemishes and acne. Model image with product for desktop. Target. Treat. Transform. Clenziderm Pore Therapy liquid exfoliant tackles blemishes and acne. Model image with product for desktop.

Bestselling Medical-Grade Skincare Products

Shop our bestsellers and find out for yourself why they are fan favorites!
Shop our bestsellers and find out for yourself why they are fan favorites!
33 items
Filters
  • Up to $230 in free gifts. Vitamin C and Sunscreen Duo, Obagi Nu-Gen Cellular Renewal Serum travel, full-size Professiona-C Serum 10%. Mobile GIF Up to $230 in free gifts. Vitamin C and Sunscreen Duo, Obagi Nu-Gen Cellular Renewal Serum travel, full-size Professiona-C Serum 10%. Desktop GIF Shop Now

    UP TO $230 VALUE

    SPEND MORE, EARN MORE FREE GIFTS

    *While supplies last. Terms & conditions apply. Shop Now
  • Allure Best of Beauty Award Seal 2025
    SERUM 20%
    SERUM 20%
    BESTSELLER
    4.6
    Rated 4.6 out of 5 stars
    221 Reviews
    PROFESSIONAL-C® ,
    SERUM 20%
    $85.00 - $155.00
  • LIFT UP & SCULPT FACIAL MOISTURIZER
    ELASTIDERM Lift Up & Sculpt Facial Moisturizer Macro Shot
    BESTSELLER
    4.7
    Rated 4.7 out of 5 stars
    109 Reviews
    ELASTIDERM® ,
    LIFT UP & SCULPT FACIAL MOISTURIZER
    $140.00
  • EYELASH ENHANCING SERUM
    OBAGI NU-CIL EYELASH ENHANCING SERUM APPLICATOR TIP
    BESTSELLER
    3.9
    Rated 3.9 out of 5 stars
    217 Reviews
    OBAGI NU-CIL® ,
    EYELASH ENHANCING SERUM
    $125.00
  • EYEBROW BOOSTING SERUM
    EYEBROW BOOSTING SERUM
    BESTSELLER
    4.1
    Rated 4.1 out of 5 stars
    144 Reviews
    OBAGI NU-CIL® ,
    EYEBROW BOOSTING SERUM
    $150.00
  • FX C-CLARIFYING SERUM
    C-Clarifying Serum Fx Open Cap
    4.3
    Rated 4.3 out of 5 stars
    24 Reviews
    OBAGI-C® FX ,
    FX C-CLARIFYING SERUM
    $145.00
  • CELLULAR RENEWAL SERUM
    Dermatologist holding Obagi Nu-Gen Cellular Renewal Serum with a quote on a blue background.
    NEW
    4.4
    Rated 4.4 out of 5 stars
    18 Reviews
    OBAGI NU-GEN™ ,
    CELLULAR RENEWAL SERUM
    Excluded from all Discounts
    $175.00
  • BIOSTIM™ SCALP SERUM
    BIOSTIM™ SCALP SERUM
    NEW
    4.3
    Rated 4.3 out of 5 stars
    36 Reviews
    OBAGI NU-CIL® ,
    BIOSTIM™ SCALP SERUM
    Excluded from all Discounts
    $125.00
  • 1.0 SMOOTHING RETINOL
    RETINOL 1.0 NEW PACKAGING
    BESTSELLER
    4.5
    Rated 4.5 out of 5 stars
    83 Reviews
    OBAGI360® ,
    1.0 SMOOTHING RETINOL
    $90.00
  • FACIAL SERUM
    Daily Hydro-Drops Facial Serum packaging transition before and after. New look, same transformational product
    BESTSELLER
    4.3
    Rated 4.3 out of 5 stars
    151 Reviews
    DAILY HYDRO-DROPS® ,
    FACIAL SERUM
    $115.00
  • FACIAL SERUM
    ELASTIDERM FIRMING FACIAL SERUM BOTTLE PACKAGING BEFORE AND AFTER. NEW LOOK, SAME TRANSFORMATIONAL PRODUCT
    BESTSELLER
    4.5
    Rated 4.5 out of 5 stars
    104 Reviews
    ELASTIDERM® ,
    FACIAL SERUM
    $220.00
  • REJUVENATING EYE GEL CREAM
    Daily Hydro-Drops Rejuvenating Eye Gel Cream before and after product image. New look, same transformational product.
    4.3
    Rated 4.3 out of 5 stars
    93 Reviews
    DAILY HYDRO-DROPS® ,
    REJUVENATING EYE GEL CREAM
    $80.00
Show More +