Obagi Nu-Derm® System

Clinically proven to help correct and improve signs of skin aging, our #1 skin care system is specially formulated to transform your complexion for beautiful, healthy-looking skin.

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Anti-aging Transformation

Skin aging is a natural process, but daily sun exposure can contribute to premature aging, slowing down the turnover of skin cells between healthy new cells and old damaged cells.

Signs of aging and photodamage:
  • Age spots
  • Fine lines and wrinkles
  • Rough skin
  • Skin laxity (loss of elasticity)
  • Erythema (redness)
  • Sallowness (complexion)
  • Hyperpigmentation (discoloration)
 
The Nu-Derm System is an anti-aging system that transforms cellular functions in all layers of the skin, helping to make skin look and act younger and healthier.
Transform Your Aging Skin
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Product Details

The Obagi Nu-Derm products are designed in a system with a specific dosage and frequency to maximize your results. Click on the products below for details on the right.

Nu-Derm System for Normal to Dry Skin
Nu-Derm System for Normal to Oily Skin
Fx
Complementary Products
As Prescribed
Nu-Derm Hydrate
Nu-Derm Hydrate

A moisturizing cream to be used as needed to soothe areas of dry, flaky skin.

Tretinoin Cream USP 0.025%, 0.05%, and 0.1%
Tretinoin Cream USP 0.025%, 0.05%, and 0.1%

A topical cream indicated for application in the treatment of acne vulgaris.

Valid prescription required.

Nu-Derm Gentle Cleanser - For Normal to Dry Skin
Nu-Derm Gentle Cleanser - For Normal to Dry Skin

Gently removes makeup and everyday impurities for a clean, fresh complexion.

Nu-Derm Foaming Gel - For Normal to Oily Skin
Nu-Derm Foaming Gel - For Normal to Oily Skin

Gently removes makeup and everyday impurities for a clean, fresh complexion.

Nu-Derm Healthy Skin Protection SPF 35
Nu-Derm Healthy Skin Protection SPF 35

A sunscreen with 9% micronized zinc oxide and 7.5% octinoxate that provides broad-spectrum UVA/UVB protection.

Nu-Derm Toner
Nu-Derm Toner

Alcohol-free, non-drying toner helps adjust the pH of your skin for increased penetration of product ingredients.

Nu-Derm Sunfader SPF 15
Nu-Derm Sunfader SPF 15

With SPF 15, helps to minimize uneven skin tone and brown spots with 4% hydroquinone.

Valid prescription required.

Nu-Derm Sun Shield Matte Broad Spectrum SPF 50
Nu-Derm Sun Shield Matte Broad Spectrum SPF 50

A sunscreen that combines UVB absorption and UVA protection in an elegant matte finish that is non-comedogenic, allergy tested, and dermatologist tested. Sheer, PABA-free, and fragrance-free for all skin types.

Nu-Derm Tolereen
Nu-Derm Tolereen

Contains 0.5% hydrocortisone for the temporary relief of itching associated with minor skin irritations and inflammation.

Nu-Derm Action
Nu-Derm Action

A moisturizing cream that helps soothe areas of dry, flaky skin.

Nu-Derm Physical UV Block SPF 32
Nu-Derm Physical UV Block SPF 32

A sunscreen with 18.5% zinc oxide that provides broad-spectrum UVA/UVB protection.

Nu-Derm Blender
Nu-Derm Blender

A unique formula containing prescription-strength hydroquinone for the gradual lightening of sun spots, age spots, and other types of discoloration.

Valid prescription required.

Nu-Derm Exfoderm Forte - For Normal to Oily Skin
Nu-Derm Exfoderm Forte - For Normal to Oily Skin

A lightweight lotion that exfoliates the top layer of the skin, removing dull, old skin cells, while promoting new skin cells for a brighter complexion.

Nu-Derm Exfoderm - For Normal to Dry Skin
Nu-Derm Exfoderm - For Normal to Dry Skin

A lightweight lotion that exfoliates the top layer of the skin, removing dull, old skin cells, while promoting new skin cells for a brighter complexion.

Nu-Derm Clear
Nu-Derm Clear

Gentle yet effective prescription-strength hydroquinone helps correct the appearance of age and sun spots for a healthier, more even complexion.

Valid prescription required.

Nu-Derm Eye Cream
Nu-Derm Eye Cream

A light moisturizing cream to help control dryness around the sensitive eye area.

Obagi Nu-Derm Clear Fx
Obagi Nu-Derm Clear Fx

A topical non-prescription formula with a non-hydroquinone skin brightener containing arbutin and antioxidants to help reduce the appearance of age and sun spots.

Available only in certain markets.

Obagi Nu-Derm Blend Fx
Obagi Nu-Derm Blend Fx

A topical non-prescription formula with a non-hydroquinone skin brightener containing arbutin, exfoliants, and antioxidants to help reduce the appearance of age and sun spots.

Available only in certain markets.

Tretinoin Cream USP 0.025%
Tretinoin Cream USP 0.025%

A topical prescription treatment for acne. Use as directed by your skin care professional.

Tretinoin Cream USP 0.05%
Tretinoin Cream USP 0.05%

A topical prescription treatment for acne. Use as directed by your skin care professional.

Tretinoin Cream USP 0.1%
Tretinoin Cream USP 0.1%

A topical prescription treatment for acne. Use as directed by your skin care professional.

Genuine Obagi

Make sure your Obagi Nu-Derm System is genuine by purchasing through an authorized channel.

Learn More

Visible Transformation

See how the Nu-Derm System can transform skin to look and act younger and healthier.1

Nu-Derm Before & After *
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Nu-Derm Before & After *
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Nu-Derm Before & After *
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Nu-Derm Before & After *
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Photos have not been retouched. Results may vary.
* Nu-Derm System + tretinoin

Renew Your Skin

The Obagi Nu-Derm System provides you with benefits you can see and feel.

nu-derm improvement in hyperpigmentation
2x greater improvement in all measurements of fine lines and wrinkles vs stand-alone treatments
  • Clinically significant improvement was seen in facial fine wrinkles, fine wrinkles around the mouth, lips, and eyes, as well as laxity
You’ll love the results of the Nu-Derm System combined with tretinoin together with common procedures
nu-derm results with tretinoin plus botox cosmetic

The Phases of Transformation

As you begin using the Nu-Derm System, your skin will undergo 4 phases of transformation.
 
Phase 1: Out With the Old (Weeks 1-6)
Promotes cellular turnover and maximizes the results of your procedure by penetrating the layers of your skin.
  • Old, dead skin cells are pushed to the surface and replaced with fresh cells
  • Itching, dryness, and redness are normal reactions as your skin adapts to the active ingredients in the system†
  • Pigmented skin cells begin to become regulated, creating a more even-toned appearance
Phase 2: In With the New (Weeks 7-12)
Smoother, softer, clearer skin is created.
  • Your skin begins producing normal, healthy cells
  • Pigment cells are distributing melanin more evenly
  • Collagen production is stimulated
  • Your skin begins to acclimate to the active ingredients of the system
Phase 3: Healthy Glow (Weeks 13-18)
Your skin cells are in the process of transformation.
  • Collagen production continues
  • Your skin is smooth, naturally hydrated, evenly colored, and more resilient
  • Your skin is becoming clearer, firmer, and tighter with improved clarity and a healthy glow
Phase 4: The New You (typically lasts indefinitely, with maintenance)
You can enjoy a complexion that’s smoother, clearer, and firmer, but remember that maintenance is crucial to long-term success!

†If you experience excessive itching, dryness, or redness, discontinue use of the system and contact your physician.

Don’t just take our word for it.
Read testimonials of real women who love the Nu-Derm System.

References: 1. OMP, Inc. Data on file. 2. Herndon JH Jr, Stephens TJ, Sigler ML. Efficacy of a tretinoin/hydroquinone-based skin health system in the treatment of facial photodamage. Cosmet Dermatol. 2006;19(4):255-262. 3. Schlessinger J, Werschler P, Kenkel J. Further enhancement of facial appearance with a hydroquinone/tretinoin skin care system in patients previously treated with botulinum toxin type A: a multicenter investigator-masked study. Poster presented at: Summer Meeting of the American Academy of Dermatology; July 29-August 2, 2009; Boston, MA.

Changing Skin. Changing Lives

Read what real women have to say about their experiences with the Obagi Nu-Derm® System. Or watch as they tell their transformation stories firsthand!

 
See Corinne's video

Meet Corinne

Years ago Corinne started to notice dark spots and fine lines, but then she found the Obagi Nu-Derm® System. Now she has her skin tone and confidence back. Corinne says Obagi Nu-Derm System helps her keep signs of aging at bay. View the video to see for yourself!

You can learn even more about Corinne’s story because she is one of our 2013 Obagi Ambassadors.

See Kristen's video

Meet Kristen

Kristen is a 33-year-old woman who has tried everything for good skin, including eating right and working out, but nothing has really helped to get rid of her sun spots…that is, until she discovered the Obagi Nu-Derm System! Hear her story and watch her transformation.

See Wendy's video

Meet Wendy

Wendy is a 47-year-old woman who wants to reverse the skin damage that has occurred over the years. Hear how she made a commitment to her skin and see the anti-aging transformation she has experienced since using the Obagi Nu-Derm System.

 
“We have used the Obagi Nu-Derm skin care system for 17 years and I have not found any other system that is comparable to the excellent results for rejuvenating and maintaining healthy skin for all skin types and conditions.”
Jody Comstock, MD
Founder/Physician,
Skin Spectrum, Tucson, AZ
 
“I started the Obagi [Nu-Derm] System about 2 weeks ago to improve melasma on my face after my dermatologist recommended that I try it.

“WOW! In only 2 weeks, most of my melasma has improved and the really tough spots I've had for years are noticeably faded! I am so delighted with your product! Even the redness and peeling (which I was warned ahead of time would happen) were very manageable.

“Some women in my office approached me the other day to ask what I was doing to my skin because it looked so smooth and radiant. I was floored! Again, thank you.”
Christine W.
Bedford, NH
 
“I purchased Obagi [Nu-Derm System] and it is wonderful. For the first time in my entire life, I am happy with my skin. I never have been before, as I've had acne and blotchy skin for so long. It's only been about 3 weeks, but I wanted you to know how happy I am with these products. Thank you.”
Stephanie R.
Vacaville, CA
 
“Thanks to such a great skin care system [Obagi Nu-Derm], my acne scars have diminished to the level I couldn't have even imagined or hoped for with skin care. My skin is more even toned and my ice pick scars are now very shallow. I'm no longer a targeted customer at the cosmetic counter. Some of my friends and family are so amazed that they have [also] gone on Obagi [Nu-Derm].”
T.K.
New York, NY
 
“I really didn’t like the texture of my skin, my pore size and I had a lot of hyperpigmentation. I was a little intimidated to have to use so many products and have to buy into some sort of system. I was skeptical. But all I can say is WOW! What a transformation.”
Paige
Orinda, CA

Steps to Healthy, Younger-looking Skin

The Nu-Derm System offers a complete, convenient protocol for treatment at home. Your physician or skin care professional will design a specific protocol that incorporates dosing, frequency, and treatment objectives for your skin.

We’ve included a standard protocol for how the products in the system are used. Click here to download the Nu-Derm System overview.

Common Questions and Answers 

How quickly will I see results when using the Nu-Derm System?
Your individual prescribed protocol and frequency of use should be determined by your skin care professional, but you can typically expect visible improvements in 4 to 6 weeks. 
 
What can I expect while using the Nu-Derm System?
You will likely experience 4 phases of transformation. Find information on what to expect during the transformation process.
 
Why is the Nu-Derm System sold exclusively by physicians?
The Nu-Derm System contains prescription-strength formulations that can be sold only through a licensed physician, such as a dermatologist or plastic surgeon.
 
What is the difference between the Nu-Derm System and products purchased from department stores, drug stores, infomercials, etc?
The products in the Nu-Derm System are clinically proven, prescription-strength ingredients that work at the cellular level to improve your skin cell function. Products purchased from a retail store are cosmetic-based products that do not contain prescription-strength ingredients. 
 
How often should I visit my dermatologist, plastic surgeon, or other skin care professional when using the Nu-Derm System?
Your dermatologist or plastic surgeon will talk with you about how often you should check in once you’ve started using the Nu-Derm System. 
 
Can the Nu-Derm System be used during pregnancy?
Please consult your physician and refer to the Important Product Information.
 
Can the Nu-Derm System be used if I will be in the sun (ie, at sporting events or at the beach)?
Keeping in mind that extended sun exposure damages the skin, it is suggested that you avoid prolonged sun exposure without protection. While on the system, you can participate in normal outdoor activity. However, your skin may be sensitive to the sun and heat. It is very important to always wear a sunscreen, like Sun Shield Matte Broad Spectrum SPF 50 in the Nu-Derm System, and reapply sun protection every few hours while exposed to the sun.
 
Why should I use all the products in the Nu-Derm System?
Each product in the Nu-Derm System is specifically designed to work together to provide you with the best results. When used as a system, the prescription-strength ingredients work to effectively balance the pH level of your skin and penetrate into the layers of your skin for superior results. Your skin care professional will guide you in using the system based on his or her assessment of your needs.
 
 
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